Postdoc (MIT)
Assistant Professor of Department of Chemistry
| Office: | YEUNG-P5306 |
|---|---|
| Phone: | +852 3442-7403 |
| Fax: | +852 3442-0522 |
| Email: | [email protected] |
| Web: | http://www.wcfulab.com |
| ORCID: | 0000-0002-7181-0057 |
| Scopus: | 55338388600 |
- Continuous flow chemistry
- Synthetic methodology
- Homogeneous catalysis
- Organic chemistry
Dr. FU received his B.Sc. in chemistry from Hong Kong Baptist University in 2013 and earned his PhD at The Hong Kong Polytechnic University (with Professor Fuk Yee Kwong) in 2018. His graduate studies focused on the development of phosphine ligands and palladium-catalyzed cross-coupling reactions. In 2017, He was selected as SciFinder Future Leader by Chemical Abstracts Service (ACS). Following a Croucher Postdoctoral Fellowship at MIT (with Professor Timothy F. Jamison) from 2018 to 2020, he returned to Hong Kong and became a research assistant professor at The Hong Kong Polytechnic University. In 2023, He was appointed as Assistant Professor of Chemistry at City University of Hong Kong.
The mission of the FU group is to address synthetic challenges through continuous flow chemistry and new technologies. Our research program seeks to employ the many benefits of continuous flow chemistry to explore the following areas,
? Discovery and application of new chemical reactions
? Continuous flow-enabled gas-liquid reactions
? Streamlined continuous flow synthesis of active pharmaceutical ingredients (APIs)
? Development of synthetic methodologies
Positions Available
We invite highly motivated and creative individuals to join our young and passionate research group. Several positions of PhD Students and Research Assistants are available. Please contact Dr. Fu ([email protected]) directly with your CV.
(*corresponding author)
- Fu, W. C.; MacQueen, P. M.; Jamison, T. F.* “Continuous Flow Strategies for Using Fluorinated Greenhouse Gases in Fluoroalkylations” Chem. Soc. Rev. 2021, 50, 7378-7394.
- Fu, W. C.; Jamison, T. F.* “Deuteriodifluoromethylation and gem-Difluoroalkenylation of Aldehydes Using ClCF2H in Continuous Flow” Angew. Chem. Int. Ed. 2020, 59, 13885-13890. (Selected as Synfact of the Month by Synfacts 2020, 16, 1001.)
- Fu, W. C.; Kwong, F. Y.* “A Denitrogenative Palladium-Catalyzed Cascade for Regioselective Synthesis of Fluorenes” Chem. Sci. 2020, 11, 1411-1417.
- Fu, W. C.; Jamison, T. F.* “Modular Continuous Flow Synthesis of Imatinib and Analogues” Org. Lett. 2019, 21, 6112-6116.
(Highlighted by Synfacts 2019, 15, 1213.) - Zhao, Q; Fu, W. C.*; Kwong, F. Y.* “Palladium-Catalyzed Regioselective Aromatic Extension of Internal Alkynes through a Norbornene-Controlled Reaction Sequence” Angew. Chem. Int. Ed. 2018, 57, 3381-3385.
(Highlighted by Synfacts 2018, 14, 0370.) - Fu, W. C.; Zheng, B; Zhao, Q.; Chan, W. T. K.; Kwong, F. Y.* “Cascade Amination and Acetone Monoarylation with Aryl Iodides by Palladium/Nobornene Cooperative Catalysis” Org. Lett. 2017, 19, 4335-4338.
- Fu, W. C.; Wang, Z.; Chan, W. T. K.; Lin, Z.*; Kwong, F. Y.* “Regioselective Synthesis of Polycyclic and Heptagon-embedded Aromatic Compounds through a Versatile π-Extension of Aryl Halides” Angew. Chem. Int. Ed. 2017, 56, 7166-7170.
- Fu, W. C.; Wu, Y; So, C. M.; Wong, S. M.; Lei, A.*; Kwong, F. Y.* “Catalytic C2-Alkenylation of Oxazoles at Parts per Million Levels of Palladium/PhMezole-Phos Complex” Org. Lett. 2016, 18, 5300-5303.
- Fu, W. C.; So, C. M.; Yuen, O. Y.; Lee, I. T. C.; Kwong, F. Y.* “Exploiting Aryl Mesylates and Tosylates in Catalytic Mono-a-Arylation of Aryl- and Heteroarylketones” Org. Lett. 2016, 18, 1872-1875. (Highlighted in Organic Chemistry Portal)
- Fu, W. C.; Zhou, Z.; Kwong, F. Y.* “Preparation of A Highly Congested Carbazoyl-Derived P,N-type Phosphine Ligand for Acetone Monoarylations” Organometallics. 2016, 35, 1553-1558. (Special Issue: Organometallics in Asia; Most Read Articles/Top 20 Most Download Articles in Apr 2016)
- Fu, W. C.; Zhou, Z.; Kwong, F. Y.* “A Benzo[c]carbazolyl-Based Phosphine Ligand for Pd-Catalyzed Tetra-ortho-substituted Biaryl Syntheses” Org. Chem. Front. 2016, 3, 273-276.
- Fu, W. C.; So, C. M.; Kwong, F. Y.* “Palladium-Catalyzed Phosphorylation of Aryl Mesylates and Tosylates” Org. Lett. 2015, 17, 5906-5909.
(Highlighted in Organic Chemistry Portal) - Fu, W. C.; So, C. M.; Chow, W. K.; Yuen, O. Y.; Kwong, F. Y.* “Design of an Indolylphosphine Ligand for Reductive Elimination-Demanding Monoarylation of Acetone Using Aryl Chlorides” Org. Lett. 2015, 17, 4612-4615.
(Highlighted in Organic Chemistry Portal)