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This course covers advanced knowledge of innate and adaptive immunity, along with the mechanisms used by pathogens to invade, replicate and spread within human and animal populations. Students will learn the basic principles underlying host-pathogen interactions and the experimental tools required to understand those interactions. On the immunology side, this course will cover the signaling pathways in the context of infection and autoimmune dysfunction. On the pathogen side, students will study a wide variety of disease agents (ranging from viruses to bacteria, protozoal, and worms pathogens) in order to identify the mechanisms they use to establish acute and chronic infection in different host species.